Cancer Immunotherapy via Gene Transfer
Researchers at Nationwide Children’s Hospital report proof-of-principle results for a new gene therapy cancer treatment. The off-the-shelf, single-dose immunotherapy serves as an alternative to CAR-T therapy and can be engineered to be on-demand.
Read more at Pediatrics Nationwide: A Single-Dose Cancer Immunotherapy via Gene Transfer.
Tree-Climbing Toads
Citizen scientists in the UK have documented common toads in tree cavities and nest boxes up to nine feet off the ground. How, and why, they got there remains a mystery.
Read my latest Animal Minds post: Tree-Climbing Toads Surprise Scientists.
Phage-Based Vaccines
Bacteriophages, or phages for short, are viruses that specifically infect bacterial cells. Phages are proven, powerful tools to treat multidrug antibiotic resistant infections. But their medical utility could go even further. A few research groups and biotech companies are exploring the potential of phages in vaccine development. And when the COVID-19 pandemic presented a challenging, new target, some researchers were ready to put phages into action.
Read my latest story for IEEE Pulse magazine: Leveraging Bacteriophages for Vaccine Development.
Baby Parrot Babbling
In a new study, researchers report that baby parrots in the wild quietly babble to themselves in their nests. The finding adds parrots to the small group of animals whose young go through a babbling stage similar to human infants.
Read the whole story at my Animal Minds blog: Baby Parrots Babble Like Human Infants.
Mendel’s Principles of Inheritance
This summer, we celebrate the 200th birthday of Gregor Mendel, known as the father of modern genetics. Mendel was an Augustinian monk in what is now the Czech Republic whose pioneering experiments uncovered the basic principles of inheritance. Between 1857 and 1864, Mendel meticulously crossbred thousands of pea plants with various traits (such as height, pea shape, and pod shape) and systematically recorded how those traits were passed from one generation to the next.
Although his scientific achievements went unrecognized during his lifetime, Mendel’s work anticipated the field of genetics, long before the discovery of DNA and genes. Our modern understanding of how traits may be inherited through generations comes from the principles of inheritance proposed by Mendel.
Read my new factsheet for the American Society of Human Genetics: Gregor Mendel and the Principles of Genetic Inheritance.