Pain Resistance in Mole-Rats
Naked mole-rats are weird. Native to East Africa, they live underground in highly ordered and hierarchical colonies with a single breeding queen, more like ants or termites than mammals. Some of their most striking physiological adaptations include an extraordinarily long lifespan (30+ years), apparent resistance to cancer, and resistance to extremely low levels of oxygen and high levels of carbon dioxide.
But it turns out naked mole-rats are not completely alone; they come from a family of weirdos. In my latest Animal Minds post, I discuss what researchers have discovered about pain insensitivity in naked mole-rats and some of their close relatives.
Read the story here: Pain Insensitivity in Mole-Rats.
Drug Overdose Deaths in the U.S.
The good news: Data released by the U.S. Centers for Disease Control and Prevention (CDC) indicate that drug overdose deaths have dropped for the first time since 1990. Between the 12-month period ending December 2017 and the 12-month period ending December 2018, there was a 5.1% decline in overdose deaths. Now the bad news: Experts still see worrisome signs in the data.
Read my latest story for IEEE Pulse magazine: Drug Overdose Deaths Decline, But Remain Historically High.
Brain Characteristics Associated with Epilepsy and Depression/Anxiety
Researchers from Nationwide Children’s Hospital found that symptoms of depression and anxiety were related to diffuse reductions in brain structure and function in youth with intractable epilepsy.
Read the whole story at Pediatrics Nationwide: Brain Characteristics Associated with Epilepsy and Internalizing Disorders.
Excess Weight Alters Results of Blood Tests in Kids
Even in children and teens, obesity has been linked to major health problems, such as diabetes and heart disease. But the effects of extra weight may show up in some tests before disease develops. Weight can affect results of routine blood tests in kids, new data show. And those results might highlight kids at risk of developing disease.
Read the whole story at Science News for Students: Excess Weight Alters Results of Blood Tests in Kids and Teens.
Gene Therapy for Rare Disorders
After decades of promise tempered by setbacks, gene therapies are nowbringing new treatment options for a variety of inherited and acquireddiseases.
Recently, clinical trials at the NIH Clinical Center and St. Jude Children’s Research Hospital have shown that gene therapy can safely correct the immune systems of children born without critical infection-fighting cells. These successes are the result of safety modifications and improvements in gene transfer efficiency and delivery fueled by basic science research. Now, as clinical progress in the field rapidly grows, gene therapies are beginning to benefit those with inherited immunodeficiencies, blood disorders, blindness, neuromuscular disease, and more.
Read my story at IEEE Pulse: Advances in Gene Therapy Offers Hope for Rare Disorders.