Gene Therapy for Spinal Muscular Atrophy
Mary Bates Mary Bates

Gene Therapy for Spinal Muscular Atrophy

In May 2019, the U.S. Food and Drug Administration (FDA) approved a gene replacement therapy for the inherited, progressive neuromuscular disease 5q-linked spinal muscular atrophy (SMA). Approval included all children with SMA under the age of two years; however, the gene therapy had only been studied in children aged up to 8 months. Now, a new study discusses safety and early outcomes in a large cohort of SMA patients under the age of two years who were treated with gene therapy.

Read more at Pediatrics Nationwide: A Multicenter Look at Gene Therapy for Spinal Muscular Atrophy.

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Wolf Leader Pairs Stay Together for Life
Mary Bates Mary Bates

Wolf Leader Pairs Stay Together for Life

This year marks the 25th anniversary of the return of wolves to Yellowstone National Park. The return not only reestablished these apex predators in part of their historic range, it has provided a unique opportunity to study the details of wolf behavior.

Researchers studying Yellowstone National Park’s wolves are learning intimate details of these predators’ lives – and finding out wolf families are a lot like our own.

Read my latest Animal Minds post: Wolf Leader Pairs Stay Together for Life.

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Heritability of Cognitive Traits in Dogs
Mary Bates Mary Bates

Heritability of Cognitive Traits in Dogs

Thousands of years of selective breeding by humans has resulted in an extraordinary degree of diversity in domestic dogs. Currently, more than 400 dog breeds are recognized internationally, running the gamut from 150-pound guard dogs to 5-pound toy companions.

Recently, genomic sequencing studies have begun to elucidate the genes behind dogs’ varied sizes and shapes. But much less is known about genetic differences in the ways dogs think and behave. Now, in a pair of new studies, researchers combine citizen science and big genomic data to examine whether there are genetically based breed differences in cognitive and behavioral traits.

Read the rest at my Animal Minds blog: Do Dog Breeds Differ in Cognitive Traits?

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The Future of Wound Care
Mary Bates Mary Bates

The Future of Wound Care

Wounds, especially chronic wounds, represent a significant clinical, social, and economic challenge. A recent retrospective analysis of Medicare beneficiaries in the United States identified that about 8.2 million people had at least one type of wound, with surgical wounds and diabetic ulcers among the most common and expensive to treat.

But even with the annual wound care products market expected to reach $15-–$22 billion by 2024, many aspects of wound care have remained unchanged for decades. Now, teams of clinicians and engineers are working on new technologies that have the potential to transform wound care, making the process smarter, faster, and more efficient.

Read the whole story at IEEE Pulse: The Future of Wound Care.

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