Alzheimer’s Association
The Alzheimer's Association is the leading voluntary health organization in Alzheimer's care, support, and research. Their mission is to end Alzheimer's and all other dementias by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support.
I write lay translations of grant proposals and research projects meant for donors and the public, some samples of which are below.
Moving Beyond Amyloid and Tau to Capture the Biological Heterogeneity of AD - Tracy Young-Pearse (August 2024)
Structural Targeting of TREM2 in Alzheimer’s Disease - Thomas Brett (August 2024)
Defining Short RNA Therapeutics that Reverse TDP-43 Proteinopathy - James Shorter (August 2024)
Measuring and Improving the Quality of Community-Based Dementia Care - Dallas Seitz (June 2024)
Towards an Equitable Alternative For Early Alzheimer’s Disease Screening - Sydney Schaefer (June 2024)
Measuring What Matters: Incorporating Person-Centered Outcomes in Adult Day Services - Tina Sadarangani (June 2024)
Development and Testing of QUALity of Interactions Inventory (QUALII) - Anju Paudel (June 2024)
METHODEM: Methodological Consensus for Complex Interventions in Dementia - Maud Graff (June 2024)
Harmonization of Tau PET Tracers to a Common Scale Using Head-to-Head Data - Guilherme Povala (May 2024)
Impaired Neuronal Cytoarchitecture in AD/ADRD - Merci Best (May 2024)
Functional Connectivity-Guided rTMS for Personalized Treatment of Apathy - Shankar Tumati (May 2024)
S14 Sphingomyelin - The Link Between Obesity and Alzheimer’s Disease - Roisin McManus (May 2024)
Understanding the Role of the Complement Pathway in Alzheimer’s Disease - Naoto Watamura (May 2024)
Dichotomy of Microglial C1q in the Progression of Alzheimer’s Disease - Tiffany Petrisko (May 2024)
Dissecting the Role of Astrocyte Network in AD-Associated Sleep Disturbance - Baoling Lai (May 2024)
Targeting Polyglutamylated Tubulin as an Early Treatment Strategy for AD - Torben Hausrat (May 2024)
Combined Lecanemab Immunotherapy and BDNF Gene Therapy for AD - Michael Castle (October 2023)
Patterns and Preferences of Home-Based Service Use for Persons with Dementia - Julia Burgdorf (October 2023)
Misalignment in Circadian Glymphatic System as Trigger of Neurodegeneration - Cristina Lanni (October 2023)
The Role of CYLD and Its Partners in Frontotemporal Dementia - Carol Dobson-Stone (October 2023)
A BCAA-Lowering Compound as a Novel Approach to Delay the Onset of AD - Andrew Shin (October 2023)
Integration of Clinical Trial MRI Data to Neuroimaging Big Data Analytics - Sindhuja Tirumalai Govindarajan (October 2023)
Alzheimer’s Risk Factors and Acculturation in Brazilian Immigrants - Sharon Sanz Simon (October 2023)
Vascular Risk, Blood Biomarker, and Brain Health in a Tri-Ethnic Population - Xiaqing Jiang (October 2023)
A Deep Learning Tool to Generalize Tau PET to Predict AD Progression - Guilherme Bauer Negrini (September 2023)
Multi-Omics Characterization of a Diverse Population in the South of Brazil - Marco Antonio De Bastiani (September 2023)
A CRISPR-Based Therapeutic for Alzheimer’s Disease - Brent Aulston (September 2023)
Uncovering the Role of SORL1 as a Key Regulator of AD Endosomal Pathology - Brooke Alisen DeRosa (September 2023)
The Role of Gender-Based Violence in Later Life Cognitive Disparities - Douglas William Hanes (September 2023)
Identifying Astrocyte-Mediated Vasomotion Underlying AD Pathogenesis - Xiaoqing Alice Zhou (September 2023)
Kv7 K+ Channels, BACE1, APP, and Alzheimer’s Disease-Related Epilepsy - Fabio Antonio Borges Vigil (September 2023)
Unraveling the Cell Type-Specific Role of of TMEM106B in Tauopathy - George Edwards III (September 2023)
Functional Analysis of the PSEN1 G206A Variant in Hispanics with Alzheimer’s Disease - Katrina Celis (September 2023)
Digital Platform for Precision Brain Health in the Bogalusa Heart Study - Ileana De Anda-Duran (September 2023)
Neuroproteasomes Underlie the Formation of Endogenous Tau/RNA Inclusions - Kalin Konrad-Vicario (September 2023)
Affective Mechanisms of the Decline in Physical Activity in Preclinical AD - Marta Stojanovic (September 2023)
Defining the Role of Adenylate Kinases in Dementia with Lewy Bodies - Namrata Kumari (September 2023)
Effects of Care and Caregiver Support on ADRD Risk of LGBTQ+ Older Adults - Nik Lampe (September 2023)
Clinical Relevance of Novel Biomarkers for Tau and Alpha-Synuclein Pathology - Oskar Hansson (August 2023)
Blood Redox Biomarker for Dementia - Gregory Brewer (August 2023)
Metabolite Signatures of Mediterranean Diet, Cognitive Change, and AD Risk - Christopher Papandreou (May 2023)
Targeting Cervical Lymphatics to Identify Biomarkers for Early AD Detection - Yijun Pan (May 2023)
Molecular Dissection of the Pathoconversion of Tau in Alzheimer’s Disease - Kassandra Ori-McKenney (May 2023)
Mechanism of Mitochondria-Targeted AD Therapeutics in Human Brain Cells - Thi Kim Oanh Nguyen (May 2023)
Genomic Admixture Effects on Neuropathology and Cognition: APOE and Beyond - Michael Naslavsky (May 2023)
Medicare Data to Identify Drugs that Reduce the Risk of Alzheimer’s Disease - Rachel Litke (May 2023)
Detecting TDP-43 Cryptic Exons Across Cell Types and Brain Regions in AD - Jonathan Ling (May 2023)
FAM222A and Tau Pathology in Alzheimer’s Disease - Jingjing Liang (May 2023)
The Role of Prolonged Fasting in the Effects of Calorie Restriction on AD - Dudley Lamming (May 2023)
Benefits and Burdens of Anticoagulation for Patients with AF and AD/ADRD - Alok Kapoor (May 2023)
Exploring the Human Microglial Secretome in Alzheimer’s Disease - Renzo Mancuso (April 2023)
Tau PET Imaging in Alzheimer’s Disease - Antoine Leuzy (April 2023)
Phenotyping of AD Based on Selective Vulnerability of Locus Coeruleus - Elouise Koops (April 2023)
Linking Vascular Cognitive Impairment and Alzheimer’s Disease Risk in Midlife - Adam Brickman (January 2023)
Detailed Proteomic Landscape of Alzheimer’s Disease - Carlos Cruchaga (January 2023)
Blood-Based Biomarkers of Vascular (Dys)function in Alzheimer’s Disease - Nilufer Ertekin-Taner (January 2023)
Controlling Microglia States for Therapeutic Benefit in Alzheimer’s Disease - Martin Kampmann (January 2023)
Cerebral Blood Flow Deficits in Neurodegenerative Disease - Chris Schaffer (January 2023)
Molecular Dissection of TDP-43 Proteinopathy in AD and its Subtypes - Dietmar Thal (January 2023)
Acceptance and Commitment Therapy for Dementia Caregivers with Poor Sleep - Yeonsu Song (December 2022)
Prenatal Stress as a Risk Factor for Alzheimer’s Disease - Bianca Ambrogina Silva (December 2022)
Exploring the Efficacy of Noninvasive 40Hz tACS Stimulation in AD Mice - Paraskevi Krashia (December 2022)
The Role of Cannabinoid Receptor 2 in the Clearance of Tau by Microglia - Valerie Joers (December 2022)
Characterization of Neuroinflammation Biomarkers in Alzheimer’s Disease - Andrea Benedet (November 2022)
In Vitro Interrogation of the Role of APOE in Microglia State and Function - Beth Stevens (November 2022)
BMP and APOE Interactions in Astrocyte Lipid Metabolism and AD Pathology - Chian-Yu Peng (November 2022)
APOE Allelic Switching to Delay or Prevent Alzheimer’s Disease - Lance Johnson (November 2022)
NHE6 Inhibition: A Novel Paradigm for Neutralizing ApoE4 Risk - Joachim Herz (November 2022)
Investigating the Protective Mechanisms of APOE2 - David Adam Brafman (November 2022)
Investigating the Cellular Response to Diverse Types of Amyloid Beta Deposits - Abhisek Mukherjee (November 2022)
Cross-Seeding Between Bacterial and Mammalian Amyloids - Rodrigo Morales (November 2022)
Arachnoid Granulation Senescence within Blacks and Whites in Aging and AD - Rupal Mehta (November 2022)
Association of Retinal Vasculature with Alzheimer’s Neuroimaging Biomarkers - Sunu Mathew (November 2022)
The Impact of SNX19 in Alzheimer’s Disease - Liang Ma (November 2022)
Repurposing Antihypertensive Drugs in Routine Care to Reduce Dementia Risk - Kevin Lu (November 2022)
Single-Cell Analysis of DNA Damage and Mutation in Alzheimer’s Disease - Michael Lodato (November 2022)
Cortical Microinfarcts: A Tool to Study Vascular Contributions to Dementia - Vasileios-Arsenios Lioutas (November 2022)
Preclinical Brain Lesions Related to Alzheimer’s Disease in Young Adults - Renata Leite (November 2022)
Linking Neuronal Hyperexcitabilty with Amyloid and Tau Pathology in AD - Alice Lam (November 2022)
Cyclooxygenase-1 PET Imaging as a Novel Neuroinflammatory Biomarker - Min-Jeong Kim (November 2022)
Subjective and Objective Cognitive Decline in Community-Dwelling Older Adults - Kelsey Thomas (November 2022)
Acetylcholine Levels Impact on Hippocampal Activity and Memory - Coralie-Anne Mosser (November 2022)
Systematic Investigation of the Impact of AD Risk Genes on Microglia States - Amanda McQuade (November 2022)
Identifying Risk Factors and Therapeutics for Cerebral Amyloid Angiopathy - Olivia Marola (November 2022)
Social Network, Loneliness, and Cognitive Decline in Diverse Older Adults - Ji Hyun Lee (November 2022)
Cerebral Hypoperfusion Induces Insulin Resistance and Exacerbates AD - Theresa Lansdell (November 2022)
Characterization of Neuroinflammation Biomarkers in Alzheimer’s Disease - Andrea Benedet (November 2022)
A Dual-Deep Learning AI Strategy to Identify Tau-Associated Genetic Variants in AD - Taeho Jo (November 2022)
Impact of Interneurons on Brain Networks in Alzheimer’s Disease - Laura Jonkman (November 2022)
A Spatial Transcriptomic Approach to Interrogating Vascular-Associated Microglia in AD (July 2022)
Assessing the Role of The ApoE Genotype in Traumatic Brain Injury - Lakiesha Williams (June 2022)
Aberrant Light Exposure, Chronodisruption and Alzheimer’s Disease - Benjamin Weger (June 2022)
Plasma Biomarkers in the Continuum from Normal Cognition through MCI to AD - Yongxiang Wang (June 2022)
The Role of TDP-43 in the Heterogeneity of Alzheimer’s Disease - Caitlin Latimer (June 2022)
Amygdala Tau Pathology in Preclinical Familial Alzheimer’s Disease - Stephanie Langella (June 2022)
Impact on Copathologies in Sporadic Early-Onset Alzheimer’s Disease - Renaud La Joie (June 2022)
Psychosocial and Cardiometabolic Modifiers of AD Risk Heritability - Zarina Kraal (June 2022)
Mapping Trajectories of Speech Metrics in Preclinical Alzheimer’s Disease - Michael Kleiman (June 2022)
Caregiving Experiences and Health of Sexual and Gender Minority Caregivers - Krystal Kittle (June 2022)
Microfluidic Screening of Alzheimer’s Risk Genes Against AB Synaptotoxicity - Devram Kilinc (June 2022)
Detecting Behaviors of Risk in Nursing Homes Using Deep Learning - Shehroz Khan (June 2022)
Sex Dependent Effects of Gut Microbiota Manipulation in Alzheimer’s Disease - Harpreet Kaur (June 2022)
OSA Treatment Impact on Brain Injury Biomarkers and Functional Connectivity - Korey Kam (June 2022)
Tobacco Control as a Tool for Lowering Risk of ADRD and ADRD-Related Disparities - Lucie Kalousova (June 2022)
Single Domain Antibody-Based Protein Degrader Targeting Alzheimer’s Disease - Yixiang Jiang (June 2022)
Exploring Mitochondrial and Nuclear DNA Variation for AD/ADRD in UK Biobank - Xueqiu Jian (June 2022)
Restoring Neuronal Function by Tau Antibody in a Tauopathy Model - Changyi Ji (June 2022)
Locus Ceruleus, Sleep Architecture, and Alzheimer’s Disease Pathology - Heidi Jacobs (June 2022)
Adaptation of an Intervention for Caregivers of Native Hawaiians with ADRD - Alexandra Malia Jackson (June 2022)
MRI Markers for Detecting Accelerated Alzheimer’s Disease After Neurotrauma - Ning Hua (June 2022)
Cellular Mechanisms of Tau Strains in Rapidly and Slowly Progressive AD - Lenka Hromadkova (June 2022)
A Pragmatic Randomized Trial Comparing Antipsychotics in Lewy Body Disease - Sarah Horn (June 2022)
Sleep and Psychosocial Factors Linked to Cognition in Alzheimer’s Disease - Emily Hokett (June 2022)
A Noninvasive Assay of Entorhinal Grid-Coding in Mild Cognitive Impairment- Paul Hill (June 2022)
Behavioral Interventions for the Treatment of Early Onset AD - Dustin Hammers (June 2022)
Brain Imaging Mechanisms Associated with Psychosis in Alzheimer’s Disease - Jesus Gomar (June 2022)
Decision Making and Advanced Planning Care in Alzheimer’s Disease - Sarah Getz (June 2022)
Enhanced Detection of Cortical Atrophy as a Biomarker of Early Decline- Kara Garcia (June 2022)
Timing and Irregularity of Daytime Napping and Alzheimer’s Disease - Chenlu Gao (June 2022)
Risk and Protective Factors for Cognitive Health of LGBTQIA+ Older Adults - Jason Flatt (June 2022)
Arterial Stiffness and Cerebral Hemodynamics Impact on Alzheimer’s Disease - Brandon Fico (June 2022)
Neurocognitive Trajectories in Older Adults with COVID-19 in the Deep South - Pariya Fazeli Wheeler (April 2022)
COVID-19 Infection Effects in Older Adults Associated to Health Disparities - Paola Garcia (April 2022)
COVID-Associated Cognitive Changes, Mood, and CSF Profiles in Older Adults - Joanna Hellmuth (April 2022)
Biomarkers of COVID-19 Induced Cognitive Loss in Diverse Older Populations - Clara Li (April 2022)
Cognitive and Neuroimaging Assessments in Post-COVID-19 Syndrome in Brazil - Carolina Marinho (April 2022)
Neurocognitive Sequelae of COVID-19 in African American Adults - Tiffany Walker (April 2022)
Long COVID Effects on Brain Cognition and Biomarkers - Eduardo Zimmer (April 2022)
NeuroCOVID: Determinants of Brain Health in Diverse Older Adults - Vanessa Zizak (April 2022)
Establishing the Role of PERK Activation on the Progression of Tauopathy - Jose Abisambra (December 2021)
Olfactory-Based Cognitive Training - Alex Bahar-Fuchs (December 2021)
Autonomic Biomarkers of Mild Behavioral Impairment in ADRD - James Bateman (December 2021)
UNC-45A Uniquely Contributes to AD Pathology - Martina Bazzaro (December 2021)
Investigating Apolipoprotein E Receptor 2 in Alzheimer's disease - Abdel Ali Belaidi (December 2021)
Exercise-Associated Modulation of Neuroinflammation in Alzheimer's Disease - Allison Birnbaum (December 2021)
Mitochondrial Replenishment as a Therapy in Alzheimer's Disease - Elvin Blanco (December 2021)
Trajectories of Vascular Disease in Aging to Predict Dementia - Daniel Bos (December 2021)
Investigation of a Novel Alzheimer's Disease-Related Microprotein - Ryan Boudreau (December 2021)
Does Fear of Dementia Influence Modifiable Risk Factors for Dementia? - Francesca Farina (December 2021)
Curbing Alzheimer’s Disease Symptoms by Robust Circadian Entrainment - Ali Guler (December 2021)
PLCg2 AD Variants in Microglial Lipid Metabolism and Calcium Signaling - Sarah Hopp (December 2021)
Developing Medication Safety Measures in Older Adults with Dementia - Minghui Li (December 2021)
Functional Characterization of New Alzheimer’s Disease-Associated Proteins - David Li-Kroeger (December 2021)
Resilience Mechanisms Underlying Dominant Inherited Alzheimer’s Disease - Jorge Llibre Guerra (December 2021)
RNA-Binding Proteins Musashi and Tau Strains in Alzheimer’s Disease - Mauro Montalbano (December 2021)
The Role of Apolipoprotein E4 in Intracellular Lipid Distribution - Lisa Munter (December 2021)
Strategies to Prevent TDP-43 Aggregation and Dipeptide-Repeat Toxicity in FTD - Hana Odeh (December 2021)
Amyloid-Beta and Tau Propagation Along Gradients of Connectivity in AD - Julie Ottoy (December 2021)
Improving Glymphatic and Microvascular Function in Alzheimer's Disease - Paulo Pires (December 2021)
Identification of RNA-Binding Protein Networks in Alzheimer’s Disease - Kimberly Raab-Graham (December 2021)
Serving the Unmet Needs of Spanish Language Family Dementia Caregivers - Liliana Ramirez Gomez (December 2021)
Neurophysiological Signatures in Preclinical Stage of Alzheimer's Disease - Kamalini Ranasinghe (December 2021)
APOE4-Regulation of Neutrophil-Microglia Crosstalk in Alzheimer’s Disease - Neta Rosenzweig (December 2021)
How to Repair the Cellular Architecture of Memory in AD - Carlo Sala Frigerio (December 2021)
Novel MicroRNAs to Treat Dementia-Related Memory Impairment in a Rat Model - Dayalan Sampath (December 2021)
Multidimensional Measurement in High Field NMR Capturing Neurodevelopment - Rita Schmidt (December 2021)
Aging in Down Syndrome: Cholinergic System and Alzheimer’s Pathology - Sepideh Shokouhi (December 2021)
Gain of Function or Loss of Function? The Role of Tau in ADRDs - Yuyu Song (December 2021)
Altered Susceptibility to Alzheimer's Disease Due to Pregnancy History - Zheng Sun (December 2021)
Pre-Loss Group Therapy for Dementia Family Care Partners at Risk for Complicated Grief - Katherine Supiano (December 2021)
Relating Longitudinal Structural Changes to AD Biomarkers and Cognition - Tammy Tran (December 2021)